Endocrine Abstracts

Introduction: Symptomatic hypoglycaemia unrelated to the treatment of diabetes is rare. As symptoms of hypoglycaemia are non-specific, investigation should only be instigated if Whipple’s triad can be fulfilled- signs and symptoms of hypoglycaemia, a recorded low plasma glucose and resolution of symptoms after treatment.Case history: A 37 year-old woman presented to the emergency department with fatigue and lightheadedness. She has modified her diet...

Background: A 59 year old man was referred to Endocrinology from Neurology with a 2 year history of hypertension, and a 1 year history of mild hypernatraemia (146–148 mmol/l) and hypokalaemia (3.2–3.4 mmol/l). He had a past history of a cerebral aneurysm and superficial siderosis. His main complaints were severe fatigue, poor balance and tinnitus. His medications at diagnosis were Amlodipine 5 mg and Sertraline 50 mg.Investigations: Blood press...

Case: A 35 year old lady was found to be hypertensive following a blood pressure check in view of her oral contraceptive pill use. Because of her young age she was referred to the Hypertension Clinic. She underwent a renal ultrasound as part of the screening for end organ damage in view of her drug-resistant hypertension. The ultrasound- and subsequent CT imaging- revealed a 2.8 cm left adrenal mass measuring 44 Hounsfield Units. She denied any palpitations or headaches but di...

Background: Vitamin D supplements are readily available without prescription. Although vitamin D toxicity is infrequent, rising use may lead to an increase in reported cases. We present a case of hypercalcemia and acute kidney injury due to excess vitamin D intakeCase: A 46-year-old woman was admitted with three-month history of lethargy, reduced oral intake, and constipation. She also experienced intermittent nausea and...

Introduction: Pituitary disorders are associated with increased mortality and morbidity. Data on the prevalence of pituitary disorders is scarce. Formal routine coding of diagnoses in outpatient endocrine practice lags behind medical coding of inpatients. Standardised coding could improve our understanding of disease burden and highlight areas of increasing need within our services.Objective: Automatically extract and assign SNOMED codes for endocrine di...

Background: Generally Endocrinologists strive to diagnose conditions biochemically prior to radiological investigation. Pituitary incidentalomas are observed in 10% of pituitary MRIs and together with stress induced hyperprolactinaemia, 10–20% of patients receive dopamine agonists (DAs) without a definite diagnosis. Menstrual imbalance is a common symptom of hyperprolactinaemia which can have multiple origins (e.g. hypothalamic, pituitary or ovarian). DAs have side effect...

Case: A 61 year old female, presented to ENT in July ’17 with 6 month history of left sided neck swelling, gradually increasing in size over the last 1 month prior to presentation. She complained of tenderness over the swelling and pain and discomfort around her left shoulder. She denied any problems with her voice, breathing or swallowing. Her past medical history consisted of recurrent UTI’s, renal stones and medullary sponge kidney. She smokes 15 cigarettes per da...

Aims: Endocrine Society (ES) acromegaly guidelines (2014) addressed complication screening. Uncontrolled acromegaly is associated with elevated cardiovascular mortality due to risk factors including hypertension (HT), diabetes mellitus (DM), obstructive sleep apnoea (OSA), and with an increased risk of colorectal cancer and polyps among other types of neoplasias. We audited our clinical practice with regards to acromegaly complication screening.Methods: ...

Aim: Endocrine Society (2016) published guidelines for hormonal replacement in hypopituitarism. Central hypothyroidism (CH) is defined as fT4 below reference range and mild CH is defined as fT4 in the low-normal range with suggestive symptoms in the context of pituitary disease. In patients with panhypopituitarism levothyroxine in doses sufficient to achieve fT4 levels in the upper half of the reference range is recommended. In our centre...

Aims: Endocrine Society (ES) acromegaly guidelines (2014) addressed complication screening. Uncontrolled acromegaly is associated with elevated cardiovascular mortality due to risk factors including hypertension (HT), diabetes mellitus (DM), obstructive sleep apnoea (OSA), and with an increased risk of colorectal cancer and polyps among other types of neoplasias. We audited our clinical practice with regards to acromegaly complication screening.Methods: ...